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Contraindications and High-Risk Populations 5-Amino-1MQ should be avoided or used only under medical supervision in: Pregnant or breastfeeding women Individuals with liver or kidney disease Patients undergoing cancer treatment Individuals with significant cardiovascular disease Those taking medications affecting methylation pathways Athletes subject to anti-doping regulations should verify regulatory compliance prior to use

5-Amino-1MQ inhibits NNMT to theoretically raise NAD+ levels, though human evidence is absent

References Kraus D, Yang Q, Kong D, et al

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Discard any vial that is cloudy, discoloured or contains particles rather than risk using it